Pregnancy-Induced Hypertension “Probably Linked” to PFOA Contamination
نویسنده
چکیده
Pregnancy-induced Hypertension " Probably linked " to PFOa Contamination Working as part of a class-action legal settlement with DuPont, a science panel appointed by the Wood County Circuit Court recently announced the first " probable link " between perfluorooctanoic acid (PFOA) released into the environment from a DuPont manufacturing plant and disease in neighboring com-munities—specifically, pregnancy-induced hypertension (PIH). The panel was ordered to return a " probable link " finding if occurrence of a disease in members of the settlement class was judged " more likely than not " to be increased by the members' PFOA exposure. With this first " probable link " designation, the next stage of the settlement kicks in, whereby DuPont must pay up to $235 million to monitor class members for any diseases for which a probable link is determined. 2 PFOA can be released into the environment during the manufacture of products such as Teflon™ nonstick coating. The chemical is present in an estimated 98% of Americans, with average blood serum levels of 5.2 ng/mL reported in the 1999−2000 National Health and Nutrition Examination Survey. 3 For people living in the 6 affected Ohio and West Virginia public water districts surrounding DuPont's Washington Works plant, serum PFOA levels averaged 32.91 ng/ mL. 4 PFOA had leached into groundwater and contaminated the Ohio River, tainting drinking water supplies.
منابع مشابه
Serum Perfluorooctanoic Acid and Perfluorooctane Sulfonate Concentrations in Relation to Birth Outcomes in the Mid-Ohio Valley, 2005–2010
BACKGROUND Previous research suggests perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) may be associated with adverse pregnancy outcomes. OBJECTIVE We conducted a population-based study of PFOA and PFOS and birth outcomes from 2005 through 2010 in a Mid-Ohio Valley community exposed to high levels of PFOA through drinking-water contamination. METHODS Women provided serum f...
متن کاملRelationship of Perfluorooctanoic Acid Exposure to Pregnancy Outcome Based on Birth Records in the Mid-Ohio Valley
BACKGROUND Perfluorooctanoic acid (PFOA) is a potential cause of adverse pregnancy outcomes, but previous studies have been limited by low exposures and small study size. OBJECTIVES Using birth certificate information, we examined the relation between estimated PFOA exposure and birth outcomes in an area of West Virginia and Ohio whose drinking water was contaminated by a chemical plant. ME...
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Background: High maternal hemoglobin (Hb) concentration was considered a risk factor for the developing of pregnancy hypertension. The purpose of this study was to determine whether high maternal Hb concentration in first trimesters associated with pregnancy induced hypertension in Iranian nulliparous women. Methods: This study was carried out in teaching hospital in Sari, Iran. Samples were ob...
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Background and purpose: Resveratrol (RSV) is a naturally polyphenolic compound found in grapes and other plant sources. It has potent free radical scavenger and antioxidative properties.The aim of this study was to evaluate the protective effect of resveratrol against Perfluorooctanoic acid (PFOA) induced mitochondrial toxicity in isolated liver mitochondria. Materials and methods: Mitochondr...
متن کاملThe Effect of Pregnancy Induced Hypertension on Complete Blood Count of Newborn
Background: Pregnancy induced hypertension is one of the most common causes of maternal and neonatal mortality and morbidity. New born delivered to mothers with hypertension are more liable for intrauterine growth retardation and may be delivered prematurely. We aimed to determine the effect of pregnancy-induced hypertension on complete blood count, gestational age and birth weight of newborn...
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عنوان ژورنال:
دوره 120 شماره
صفحات -
تاریخ انتشار 2012